Galr2^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Galr2^tm1Dgen
• Name: galanin receptor 2; targeted mutation 1, Deltagen
• MGI ID: MGI:3622325
• Synonyms: Galr2^-
• Gene: Galr2 Location: Chr11:116171765-116174764 bp, + strand Genetic Position: Chr11, 81.1 cM
• Alliance: Galr2^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:107144
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A neomycin resistance cassette was inserted into the intron of the locus. RT-PCR confirmed inactivation of the gene. (J:107144)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Galr2 Mutation: 31 strains or lines available

References

• Original: J:107144 Shi TJ, et al., Sensory neuronal phenotype in galanin receptor 2 knockout mice: focus on dorsal root ganglion neurone development and pain behaviour. Eur J Neurosci. 2006 Feb;23(3):627-36
• All: 2 reference(s)