Grik1^tm2Sfh
Targeted Allele Detail

Summary

• Symbol: Grik1^tm2Sfh
• Name: glutamate receptor, ionotropic, kainate 1; targeted mutation 2, Stephen F Heinemann
• MGI ID: MGI:3623113
• Synonyms: GluR5-R^loxP
• Gene: Grik1 Location: Chr16:87692788-88087153 bp, - strand Genetic Position: Chr16, 50.23 cM
• Alliance: Grik1^tm2Sfh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:57983
• Parent Cell Line: CCE/EK.CCE (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: A targeting construct was used to insert a Q636R mutation in the locus as well as a PGK-TK cassette and a floxed neo cassette later removed via cre-mediated recombination. (J:57983)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Grik1 Mutation: 53 strains or lines available

References

• Original: J:57983 Sailer A, et al., Generation and analysis of GluR5(Q636R) kainate receptor mutant mice. J Neurosci. 1999 Oct 15;19(20):8757-64
• All: 2 reference(s)