Avpr1a^tm1Gzt
Targeted Allele Detail

Summary

• Symbol: Avpr1a^tm1Gzt
• Name: arginine vasopressin receptor 1A; targeted mutation 1, Gozoh Tsujimoto
• MGI ID: MGI:3623418
• Synonyms: V1a-, V1aR^-, V1aR KO
• Gene: Avpr1a Location: Chr10:122284404-122289357 bp, + strand Genetic Position: Chr10, 70.36 cM, cytoband D3
• Alliance: Avpr1a^tm1Gzt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:107607
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector was designed to replace parts of the first exon and the first intron with a neomycin resistance cassette. RT-PCR failed to detect transcripts in any mutant tissues that were examined. (J:110099)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Avpr1a Mutation: 35 strains or lines available

References

• Original: J:107607 Egashira N, et al., V1a receptor knockout mice exhibit impairment of spatial memory in an eight-arm radial maze. Neurosci Lett. 2004 Feb 19;356(3):195-8
• All: 25 reference(s)