Ptgdr2^tm1Byl
Targeted Allele Detail

Summary

• Symbol: Ptgdr2^tm1Byl
• Name: prostaglandin D2 receptor 2; targeted mutation 1, Baiyong Li
• MGI ID: MGI:3623476
• Synonyms: CRTH2^-
• Gene: Ptgdr2 Location: Chr19:10914524-10919875 bp, + strand Genetic Position: Chr19, 7.4 cM
• Alliance: Ptgdr2^tm1Byl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:107519
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector was designed to replace 1.8 kb of the locus, including bases 1-1085, with a PGK-neo cassette. Transcript was not detected in any tissues tested by RT-PCR. (J:107519)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptgdr2 Mutation: 15 strains or lines available

References

• Original: J:107519 Chevalier E, et al., Cutting edge: chemoattractant receptor-homologous molecule expressed on Th2 cells plays a restricting role on IL-5 production and eosinophil recruitment. J Immunol. 2005 Aug 15;175(4):2056-60
• All: 1 reference(s)