Or10a4^tm1Rax
Targeted Allele Detail

Summary

• Symbol: Or10a4^tm1Rax
• Name: olfactory receptor family 10 subfamily A member 4; targeted mutation 1, Richard Axel
• MGI ID: MGI:3623580
• Synonyms: P2-Deletion-IRES-tau-lacZ, P2delta-IRES-taulacZ
• Gene: Or10a4 Location: Chr7:106696674-106697621 bp, + strand Genetic Position: Chr7, 56.1 cM, cytoband F2
• Alliance: Or10a4^tm1Rax page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:107717
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A tau-lacZ-tk-neo cassette replaced the coding sequence. The tk-neo was flanked with loxP sites and removed in ES cells via transient cre expression. X-gal staining indicated expression of the mutant allele in subpopulations of sensory neurons whose dendrites, cell bodies, and axons exhibit staining. (J:107717)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Or10a4 Mutation: 22 strains or lines available

References

• Original: J:107717 Wang F, et al., Odorant receptors govern the formation of a precise topographic map. Cell. 1998 Apr 3;93(1):47-60
• All: 1 reference(s)