Ctnna2^tm1Mta
Targeted Allele Detail

Summary

• Symbol: Ctnna2^tm1Mta
• Name: catenin alpha 2; targeted mutation 1, Masatoshi Takeichi
• MGI ID: MGI:3623589
• Synonyms: alphaN-cat^-
• Gene: Ctnna2 Location: Chr6:76858620-77956682 bp, - strand Genetic Position: Chr6, 33.54 cM, cytoband B3-D
• Alliance: Ctnna2^tm1Mta page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:107709
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: An IRES-EGFP-pA cassette was inserted into exon 2. Mutants failed to express either long or short isoforms of protein as shown by Western blot analysis. (J:107709)

Disease models

Expression

In Mice Carrying this Mutation:	33 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ctnna2 Mutation: 53 strains or lines available

References

• Original: J:107709 Togashi H, et al., Cadherin regulates dendritic spine morphogenesis. Neuron. 2002 Jul 3;35(1):77-89
• All: 5 reference(s)