Lsr^tm1Mdar
Targeted Allele Detail

Summary

• Symbol: Lsr^tm1Mdar
• Name: lipolysis stimulated lipoprotein receptor; targeted mutation 1, Michel Darmon
• MGI ID: MGI:3623628
• Synonyms: Lsr^-
• Gene: Lsr Location: Chr7:30657195-30672889 bp, - strand Genetic Position: Chr7, 19.27 cM, cytoband A3
• Alliance: Lsr^tm1Mdar page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:92354
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector was designed to replace sequence between the 5' end of exon 2 and the 3' end of exon 5 with a betagalactosidase and a neomycin resistance cassette. (J:92354)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lsr Mutation: 28 strains or lines available

References

• Original: J:92354 Mesli S, et al., Distribution of the lipolysis stimulated receptor in adult and embryonic murine tissues and lethality of LSR-/- embryos at 12.5 to 14.5 days of gestation. Eur J Biochem. 2004 Aug;271(15):3103-14
• All: 5 reference(s)