Zhx2^BALB/cJ
Spontaneous Allele Detail

Summary

• Symbol: Zhx2^BALB/cJ
• Name: zinc fingers and homeoboxes 2; BALB/cJ
• MGI ID: MGI:3623885
• Synonyms: Afr1^b, raf^BALB/c, Zhx2^Afr1
• Gene: Zhx2 Location: Chr15:57558063-57703228 bp, + strand Genetic Position: Chr15, 24.01 cM
• Alliance: Zhx2^BALB/cJ page

Mutation origin

• Strain of Origin: BALB/cJ

Mutation description

• Allele Type: Spontaneous (Hypomorph)
• Mutation: Transposon insertion
• Mutation details: A class II retrotransposon belonging to the MERV-K family was inserted into intron 1. Sequence analysis demonstrated the MERV element contained two LTRs that were 317 bp in length and an EcoRI site 655 bp from the 3' end. This BALB/cJ specific sequence has been deposited in NCBI as EU233786. Northern blot detected chimeric transcripts from these animals. (J:96258, J:157062)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zhx2 Mutation: 34 strains or lines available

References

• Original: J:5803 Olsson M, et al., Genetic control of alpha-fetoprotein synthesis in the mouse. J Exp Med. 1977 Apr 1;145(4):819-27
• All: 7 reference(s)