Pdlim2^tm1Gru
Targeted Allele Detail

Summary

• Symbol: Pdlim2^tm1Gru
• Name: PDZ and LIM domain 2; targeted mutation 1, Michael J Grusby
• MGI ID: MGI:3623895
• Gene: Pdlim2 Location: Chr14:70401667-70415130 bp, - strand Genetic Position: Chr14, 36.26 cM
• Alliance: Pdlim2^tm1Gru page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:99108
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A neomycin resistance gene was inserted into exon 2. Absence of transcript and protein was confirmed by Northern and Western blot, respectively. (J:99108)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pdlim2 Mutation: 32 strains or lines available

References

• Original: J:99108 Tanaka T, et al., SLIM Is a Nuclear Ubiquitin E3 Ligase that Negatively Regulates STAT Signaling. Immunity. 2005 Jun;22(6):729-36
• All: 5 reference(s)