Palld^tm1Zgwg
Targeted Allele Detail

Summary

• Symbol: Palld^tm1Zgwg
• Name: palladin, cytoskeletal associated protein; targeted mutation 1, Zhugang Wang
• MGI ID: MGI:3623949
• Gene: Palld Location: Chr8:61964467-62355724 bp, - strand Genetic Position: Chr8, 31.23 cM, cytoband B3.3
• Alliance: Palld^tm1Zgwg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:100650
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting construct was designed to replace exons 17 and 18 and part of 19, sequence encoding the three Ig-like domains, with a PGK-neo cassette. Western blot failed to detect either the main isoform. (J:100650)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Palld Mutation: 61 strains or lines available

References

• Original: J:100650 Luo H, et al., Disruption of palladin results in neural tube closure defects in mice. Mol Cell Neurosci. 2005 Aug;29(4):507-15
• All: 5 reference(s)