Fbxw7as1^tm1Opaz
Targeted Allele Detail

Summary

• Symbol: Fbxw7as1^tm1Opaz
• Name: F-box and WD-40 domain protein 7 antisense transcript 1; targeted mutation 1, Nelson Ruiz-Opazo
• MGI ID: MGI:3623969
• Synonyms: DEspR^-
• Gene: Fbxw7as1 Location: Chr3:84872363-84872887 bp, - strand Genetic Position: Chr3, 37.7 cM
• Alliance: Fbxw7as1^tm1Opaz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:103174
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 300 bp sequence containing the 3' end was replaced with a PGK-neomycin resistance cassette, resulting in the deletion of amino acids 81-127. (J:103174)

Expression

In Mice Carrying this Mutation:	6 assay results
In Structures Affected by this Mutation:	9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fbxw7as1 Mutation: 0 strains or lines available

References

• Original: J:103174 Herrera VL, et al., Embryonic lethality in Dear gene-deficient mice: new player in angiogenesis. Physiol Genomics. 2005 Nov 17;23(3):257-68
• All: 4 reference(s)