L1cam^tm1(tTA)Msch
Targeted Allele Detail

Summary

• Symbol: L1cam^tm1(tTA)Msch
• Name: L1 cell adhesion molecule; targeted mutation 1, Melitta Schachner
• MGI ID: MGI:3624137
• Synonyms: fL1^-, L1cam^tm1(tTA)Ubar, L1/tTA
• Gene: L1cam Location: ChrX:72897384-72924843 bp, - strand Genetic Position: ChrX, 37.43 cM, cytoband A6-B
• Alliance: L1cam^tm1(tTA)Msch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:107878
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Transactivator)
• Mutation: Insertion
• Mutation details: A tetracycline-controlled transactivator was inserted into the second exon of the locus. The null mutation was confirmed by immunoblot of brain tissue. (J:107878)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any L1cam Mutation: 12 strains or lines available

References

• Original: J:107878 Rolf B, et al., Severe hydrocephalus in L1-deficient mice. Brain Res. 2001 Feb 9;891(1-2):247-52
• All: 7 reference(s)