In(4)56Rk
Radiation induced Allele Detail

Summary

• Symbol: In(4)56Rk
• Name: inversion, Chr 4, Roderick 56
• MGI ID: MGI:3624517
• Synonyms: Gbn1^Rd4, Rd4
• Gene: In(4)56Rk Location: unknown Genetic Position: Chr4, Syntenic

Mutation origin

• Strain of Origin: (DBA/2J x C57BL/6J)F1

Mutation description

• Allele Type: Radiation induced (Null/knockout)
• Mutations: Intragenic deletion, Inversion
• In(4)56Rk involves 1 genes/genome features (Gnb1) View all
• Mutation details: This is a large inversion on Chromosome 4 which arose in a DBA/2J male exposed to 1000R of radiation. It covers most of chromosome 4 with the breakpoints in G bands 4A1 and 4E2. The distal breakpoint of the inversion is in the second intron of the Gnb1 gene and the proximal breakpoint lies within the centromere. (J:41514, J:108450)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any In(4)56Rk Mutation: 1 strain or line available

Notes

This inversion is homozygous lethal.

References

• Original: J:23392 Beechey CV, List of Chromosome Anomalies. Mouse Genome. 1994;92:336-47
• All: 7 reference(s)