Slc2a1^tm1Dcdv
Targeted Allele Detail

Summary

• Symbol: Slc2a1^tm1Dcdv
• Name: solute carrier family 2 (facilitated glucose transporter), member 1; targeted mutation 1, Darryl C De Vivo
• MGI ID: MGI:3624543
• Synonyms: Glut-1^-
• Gene: Slc2a1 Location: Chr4:118966001-118994527 bp, + strand
• Alliance: Slc2a1^tm1Dcdv page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:108250
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector was used to replace the promoter region and exon 1 with a neomycin resistance gene. (J:108250)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc2a1 Mutation: 60 strains or lines available

References

• Original: J:108250 Wang D, et al., A mouse model for Glut-1 haploinsufficiency. Hum Mol Genet. 2006 Apr 1;15(7):1169-79
• All: 6 reference(s)