Pawr^tm1.1Yshi
Targeted Allele Detail

Summary

• Symbol: Pawr^tm1.1Yshi
• Name: PRKC, apoptosis, WT1, regulator; targeted mutation 1.1, Yang Shi
• MGI ID: MGI:3624677
• Synonyms: mpar-4
• Gene: Pawr Location: Chr10:108167982-108250101 bp, + strand Genetic Position: Chr10, 56.43 cM, cytoband D1
• Alliance: Pawr^tm1.1Yshi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:108228
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exons 4 and 5 were removed via cre mediated recombination. Western blot confirmed absence of protein in mutants. (J:108228)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pawr Mutation: 20 strains or lines available

References

• Original: J:108228 Affar el B, et al., Targeted ablation of Par-4 reveals a cell type-specific susceptibility to apoptosis-inducing agents. Cancer Res. 2006 Apr 1;66(7):3456-62
• All: 1 reference(s)