Dach2^tm1.1Mrd
Targeted Allele Detail

Summary

• Symbol: Dach2^tm1.1Mrd
• Name: dachshund family transcription factor 2; targeted mutation 1.1, Graeme Mardon
• MGI ID: MGI:3625291
• Gene: Dach2 Location: ChrX:112207207-112746083 bp, + strand Genetic Position: ChrX, 49.13 cM
• Alliance: Dach2^tm1.1Mrd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:106771
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Cre mediated resulted in the excision of exon 1, which contains the translational start site and domain 1. (J:106771)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dach2 Mutation: 10 strains or lines available

References

• Original: J:106771 Davis RJ, et al., Mouse Dach2 mutants do not exhibit gross defects in eye development or brain function. Genesis. 2006 Feb;44(2):84-92
• All: 4 reference(s)