Cd248^tm1Huso
Targeted Allele Detail

Summary

• Symbol: Cd248^tm1Huso
• Name: CD248 antigen, endosialin; targeted mutation 1, David L Huso
• MGI ID: MGI:3625491
• Gene: Cd248 Location: Chr19:5118106-5120668 bp, + strand Genetic Position: Chr19, 4.24 cM
• Alliance: Cd248^tm1Huso page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:107172
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance gene replaced most of the single coding exon of the locus. RT-PCR confirmed absence of transcript in mutant colon, liver and skin samples. (J:107172)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd248 Mutation: 24 strains or lines available

References

• Original: J:107172 Nanda A, et al., Tumor endothelial marker 1 (Tem1) functions in the growth and progression of abdominal tumors. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3351-6
• All: 12 reference(s)