Tg(Camk2a-Prkaca)426Tabe
Transgene Detail

Summary

• Symbol: Tg(Camk2a-Prkaca)426Tabe
• Name: transgene insertion 426, Ted Abel
• MGI ID: MGI:3626071
• Synonyms: CaMKII-R(AB), R(AB), R(AB)-2
• Transgene: Tg(Camk2a-Prkaca)426Tabe Location: unknown
• Alliance: Tg(Camk2a-Prkaca)426Tabe page

Transgene origin

• Strain of Origin: (C57BL/6J x CBA/J)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Camk2a-Prkaca)426Tabe expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Prkaca (MGI:97592)

• Mutation details: The cAMP-dependent protein kinase A (PKA or PRKACA) RIalpha regulatory subunit, R(AB), was mutated at both cAMP binding sites and placed under control of the mouse Camk2a promoter. (J:38837)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:38837 Abel T, et al., Genetic demonstration of a role for PKA in the late phase of LTP and in hippocampus-based long-term memory. Cell. 1997 Mar 7;88(5):615-26
• All: 10 reference(s)