Nnt^C57BL/6J
Spontaneous Allele Detail

Summary

• Symbol: Nnt^C57BL/6J
• Name: nicotinamide nucleotide transhydrogenase; C57BL/6J
• MGI ID: MGI:3626282
• Synonyms: Ant1^-
• Gene: Nnt Location: Chr13:119472063-119545793 bp, - strand Genetic Position: Chr13, 67.21 cM, cytoband D2
• Alliance: Nnt^C57BL/6J page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Spontaneous (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele contains a stretch of 17,814 bp missing between exons 6 and 12. RT-PCR demonstrated cDNA corresponding to exons 7-11 was absent. Mature protein was not detected in these mutants. (J:106692, J:108213)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Nnt Mutation: 64 strains or lines available

References

• Original: J:108213 Huang TT, et al., Genetic modifiers of the phenotype of mice deficient in mitochondrial superoxide dismutase. Hum Mol Genet. 2006 Apr 1;15(7):1187-94
• All: 39 reference(s)