Bmp7^tm6(cre)Rob
Targeted Allele Detail

Summary

• Symbol: Bmp7^tm6(cre)Rob
• Name: bone morphogenetic protein 7; targeted mutation 6, Elizabeth J Robertson
• MGI ID: MGI:3626288
• Synonyms: Bmp7^cre
• Gene: Bmp7 Location: Chr2:172709805-172782114 bp, - strand Genetic Position: Chr2, 95.54 cM
• Alliance: Bmp7^tm6(cre)Rob page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:108109
• Parent Cell Line: CCE/EK.CCE (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Bmp7^tm6(cre)Rob expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Bmp7 (MGI:103302)

• Mutation details: A cassette containing an IRES-cre and FRT-flanked hygro was inserted into exon 1 of the locus. The hygro was removed via FLP mediated recombination. (J:108109)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Bmp7 (mouse) Summary of all recombinase alleles driven by Bmp7. Comparative matrix view of recombinase activities Alliance mouse Bmp7 gene page

Expression

In Mice Carrying this Mutation:

81 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bmp7 Mutation: 37 strains or lines available

References

• Original: J:108109 Oxburgh L, et al., TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population. Development. 2004 Sep;131(18):4593-605
• All: 4 reference(s)