Fezf1^tm1Hibi
Targeted Allele Detail

Summary

• Symbol: Fezf1^tm1Hibi
• Name: Fez family zinc finger 1; targeted mutation 1, Masahiko Hibi
• MGI ID: MGI:3626294
• Synonyms: Fez^-
• Gene: Fezf1 Location: Chr6:23245043-23248361 bp, - strand Genetic Position: Chr6, 10.55 cM, cytoband A3
• Alliance: Fezf1^tm1Hibi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:107405
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A PGK-neo cassette replaced sequences encoding amino acids 1-350. (J:107405)

Expression

In Mice Carrying this Mutation:	2 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fezf1 Mutation: 31 strains or lines available

Notes

ES cell line = R1 ((129X1/SvJ x 129S1/Sv)F1-Kitl<+>) or EB3 (129P2/OlaHsd). EB3 cells, derived from E14TG2a, carry one allele of Pou5f1 that has been inactivated via targeted integration of E14TG2a ES cells with an IRESBSDpA selection cassette. J:107405 does not mention whether the null allele of Pou5f1 is also present in the line of mice created.

References

• Original: J:107405 Hirata T, et al., Zinc-finger gene Fez in the olfactory sensory neurons regulates development of the olfactory bulb non-cell-autonomously. Development. 2006 Apr;133(8):1433-43
• All: 4 reference(s)