Abcb7^tm1.1Mdf
Targeted Allele Detail

Summary

• Symbol: Abcb7^tm1.1Mdf
• Name: ATP-binding cassette, sub-family B member 7; targeted mutation 1.1, Mark D Fleming
• MGI ID: MGI:3628655
• Synonyms: Abcb7^-
• Gene: Abcb7 Location: ChrX:103324263-103457462 bp, - strand Genetic Position: ChrX, 46.58 cM, cytoband C-D
• Alliance: Abcb7^tm1.1Mdf page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:106838
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Cre mediated recombination was used to remove exons 9 and 10 from the locus. (J:106838)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Abcb7 Mutation: 13 strains or lines available

References

• Original: J:106838 Pondarre C, et al., The mitochondrial ATP-binding cassette transporter Abcb7 is essential in mice and participates in cytosolic iron-sulfur cluster biogenesis. Hum Mol Genet. 2006 Mar 15;15(6):953-64
• All: 1 reference(s)