Nme1^tm1Jyd
Targeted Allele Detail

Summary

• Symbol: Nme1^tm1Jyd
• Name: NME/NM23 nucleoside diphosphate kinase 1; targeted mutation 1, Jean-Yves Daniel
• MGI ID: MGI:3628812
• Synonyms: m1^-, Nm23-M1^-
• Gene: Nme1 Location: Chr11:93849751-93859341 bp, - strand Genetic Position: Chr11, 58.89 cM
• Alliance: Nme1^tm1Jyd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:109190
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A promoterless betagal was inserted into the locus such that the ATG in exon 2 was replaced. Northern blot failed to detect transcript in mutant liver extracts. Reporter expression was detected in embryos in the epithelial layer. (J:109190)

Expression

In Mice Carrying this Mutation:	32 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nme1 Mutation: 26 strains or lines available

References

• Original: J:109190 Arnaud-Dabernat S, et al., Knockout mice as model systems for studying nm23/NDP kinase gene functions. Application to the nm23-M1 gene. J Bioenerg Biomembr. 2003 Feb;35(1):19-30
• All: 6 reference(s)