Kat6a^tm1Iki
Targeted Allele Detail

Summary

• Symbol: Kat6a^tm1Iki
• Name: K(lysine) acetyltransferase 6A; targeted mutation 1, Issay Kitabayashi
• MGI ID: MGI:3629032
• Synonyms: MOZ-
• Gene: Kat6a Location: Chr8:23349551-23433275 bp, + strand Genetic Position: Chr8, 11.42 cM
• Alliance: Kat6a^tm1Iki page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:108699
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: Insertion of a neomycin resistance cassette into exon 2, which contains the first methionine ATG, disrupted the gene. Western blot analysis of E12.5 embryo lysates did not detect protein. (J:108699)

Expression

In Mice Carrying this Mutation:	39 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kat6a Mutation: 69 strains or lines available

References

• Original: J:108699 Katsumoto T, et al., MOZ is essential for maintenance of hematopoietic stem cells. Genes Dev. 2006 May 15;20(10):1321-30
• All: 4 reference(s)