Tg(ITGAM-cre)2781Gkl
Transgene Detail

Summary

• Symbol: Tg(ITGAM-cre)2781Gkl
• Name: transgene insertion 2781, George Kollias
• MGI ID: MGI:3629092
• Synonyms: CD11b-Cre, Tg(ITGAM-cre)1Dwc
• Transgene: Tg(ITGAM-cre)2781Gkl Location: unknown
• Alliance: Tg(ITGAM-cre)2781Gkl page

Transgene origin

• Strain of Origin: (CBA x C57BL/6)F1

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(ITGAM-cre)2781Gkl expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  ITGAM (3684)

  Itgam

  (MGI:96607)

• Mutation details: A 1.7 kb DNA fragment of the human integrin alpha M promoter was used to drive expression of cre recombinase in the myeloid lineage. (J:109131)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	ITGAM (human) Summary of all recombinase alleles driven by ITGAM. Comparative matrix view of recombinase activities Alliance human ITGAM gene page

Disease models

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:109131 Boillee S, et al., Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia. Science. 2006 Jun 2;312(5778):1389-92
• All: 33 reference(s)