Dbnl^tm1Jwnd
Targeted Allele Detail

Summary

• Symbol: Dbnl^tm1Jwnd
• Name: drebrin-like; targeted mutation 1, Jurgen Wienands
• MGI ID: MGI:3629216
• Synonyms: mabp1^-
• Gene: Dbnl Location: Chr11:5738488-5750962 bp, + strand Genetic Position: Chr11, 3.87 cM
• Alliance: Dbnl^tm1Jwnd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:109363
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: BALB/c

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 and 3 were replaced with a neomycin resistance gene in opposite orientation by homologous recombination. Protein expression was not detected in mutant brain or spleen in immunoblot analysis. (J:109363)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dbnl Mutation: 27 strains or lines available

References

• Original: J:109363 Connert S, et al., SH3P7/mAbp1 deficiency leads to tissue and behavioral abnormalities and impaired vesicle transport. EMBO J. 2006 Apr 19;25(8):1611-22
• All: 3 reference(s)