Cst5^tm1Hkaw
Targeted Allele Detail

Summary

• Symbol: Cst5^tm1Hkaw
• Name: cystatin D; targeted mutation 1, Hiroshi Kawaguchi
• MGI ID: MGI:3629665
• Synonyms: Cst10^-
• Gene: Cst5 Location: Chr2:149247242-149252217 bp, + strand Genetic Position: Chr2, 73.8 cM, cytoband G
• Alliance: Cst5^tm1Hkaw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:109550
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector was designed to replace exon 1 with a pgk-neo cassette. Neither transcripts nor protein was detected in mutant rib cartilage. (J:109550)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cst5 Mutation: 12 strains or lines available

References

• Original: J:109550 Yamada T, et al., Carminerin contributes to chondrocyte calcification during endochondral ossification. Nat Med. 2006 Jun;12(6):665-70
• All: 1 reference(s)