Tg(NPHS2-rtTA2*M2)1Jbk
Transgene Detail

Summary

• Symbol: Tg(NPHS2-rtTA2*M2)1Jbk
• Name: transgene insertion 1, Jeffrey B Kopp
• MGI ID: MGI:3629962
• Synonyms: 2.5P-rtTA, podocin-rtTA, Tg(NPHS2-rtTA)1Jbk
• Transgene: Tg(NPHS2-rtTA2*M2)1Jbk Location: unknown
• Alliance: Tg(NPHS2-rtTA2*M2)1Jbk page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Mutation details: The rtTA gene was placed under the control of the human NPHS2 gene. The resulting transgene is expressed in the kidney when induced by doxycycline. (J:109826)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:109826 Shigehara T, et al., Inducible podocyte-specific gene expression in transgenic mice. J Am Soc Nephrol. 2003 Aug;14(8):1998-2003
• All: 50 reference(s)