Dkk2^tm1Lmgd
Targeted Allele Detail

Summary

• Symbol: Dkk2^tm1Lmgd
• Name: dickkopf WNT signaling pathway inhibitor 2; targeted mutation 1, Laboratory of Mammalian Genes and Development, Heiner Westphal
• MGI ID: MGI:3639316
• Synonyms: Dkk2^-
• Gene: Dkk2 Location: Chr3:131791053-131886065 bp, + strand Genetic Position: Chr3, 61.32 cM, cytoband H2
• Alliance: Dkk2^tm1Lmgd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:109481
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The entire first exon was replaced with a PGK-neo cassette. (J:109481)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dkk2 Mutation: 26 strains or lines available

References

• Original: J:109481 Mukhopadhyay M, et al., Dkk2 plays an essential role in the corneal fate of the ocular surface epithelium. Development. 2006 Jun;133(11):2149-54
• All: 3 reference(s)