Fgf8^tm2Moon
Targeted Allele Detail

Summary

• Symbol: Fgf8^tm2Moon
• Name: fibroblast growth factor 8; targeted mutation 2, Anne M Moon
• MGI ID: MGI:3639320
• Synonyms: Fgf8^c
• Gene: Fgf8 Location: Chr19:45725237-45731354 bp, - strand Genetic Position: Chr19, 38.75 cM, cytoband C3-D
• Alliance: Fgf8^tm2Moon page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:109475
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 4, an frt-flanked neo and a second loxP site was inserted into the 3' UTR. (J:109475)

Expression

In Mice Carrying this Mutation:	54 assay results
In Structures Affected by this Mutation:	11 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgf8 Mutation: 21 strains or lines available

References

• Original: J:109475 Park EJ, et al., Required, tissue-specific roles for Fgf8 in outflow tract formation and remodeling. Development. 2006 Jun;133(12):2419-33
• All: 12 reference(s)