Fyn^tm1Fam
Targeted Allele Detail

Summary

• Symbol: Fyn^tm1Fam
• Name: Fyn proto-oncogene; targeted mutation 1, F Arthur McMorris
• MGI ID: MGI:3639430
• Synonyms: FynK296R
• Gene: Fyn Location: Chr10:39245735-39441377 bp, + strand Genetic Position: Chr10, 20.51 cM
• Alliance: Fyn^tm1Fam page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:109485
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A K296R mutation was engineered into the locus by homologous recombination. (J:109485)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fyn Mutation: 39 strains or lines available

References

• Original: J:109485 Sperber BR, et al., A unique role for Fyn in CNS myelination. J Neurosci. 2001 Mar 15;21(6):2039-47
• All: 1 reference(s)