Tg(Mef2c-cre)2Blk
Transgene Detail

Summary

• Symbol: Tg(Mef2c-cre)2Blk
• Name: transgene insertion 2, Brian L Black
• MGI ID: MGI:3639735
• Synonyms: AHF-Cre, Mef2c-AHFCre, mef2c-AHF-Cre line 200A
• Transgene: Tg(Mef2c-cre)2Blk Location: unknown
• Alliance: Tg(Mef2c-cre)2Blk page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Mef2c-cre)2Blk expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Mef2c

• Mutation details: The Mef2c anterior heart field enhancer and promoter (AHF) was cloned into a cre expression plasmid with the cre cDNA and the SV40 splice sequence and the polyA signal sequence. The Mef2c-AHF-Cre fragment was injected into male pronuclei of fertilized oocytes. Three founder lines were initially characterized and line 200A was used for further analysis. (J:103545)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Mef2c (species not specified) Summary of all recombinase alleles driven by Mef2c. Comparative matrix view of recombinase activities

Disease models

Expression

In Mice Carrying this Mutation:

166 assay results 6 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:103545 Verzi MP, et al., The right ventricle, outflow tract, and ventricular septum comprise a restricted expression domain within the secondary/anterior heart field. Dev Biol. 2005 Nov 1;287(1):134-45
• All: 86 reference(s)