Ddr2^slie
Spontaneous Allele Detail

Summary

• Symbol: Ddr2^slie
• Name: discoidin domain receptor family, member 2; smallie
• MGI ID: MGI:3640081
• Gene: Ddr2 Location: Chr1:169799876-169938331 bp, - strand Genetic Position: Chr1, 76.84 cM, cytoband H1-H5
• Alliance: Ddr2^slie page

Mutation origin

• Strain of Origin: BKSChpLt.Cg-Tg(Ins2-Cpe)1Lt Cpe^fat/LtJng

Mutation description

• Allele Type: Spontaneous
• Mutation: Intragenic deletion
• Mutation details: The mutation is a deletion of approximately 150kb encompassing most of the Ddr2 gene, of which genomic PCR analysis failed to amplify exons 1-17; exon 18 of this gene and the final exon of the proximal gene, Hsd17b7, both were amplified. (J:134371)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ddr2 Mutation: 61 strains or lines available

References

• Original: J:134371 Kano K, et al., A novel dwarfism with gonadal dysfunction due to loss-of-function allele of the collagen receptor gene, Ddr2, in the mouse. Mol Endocrinol. 2008 Aug;22(8):1866-80
• All: 14 reference(s)