Septin5^tm1Bld
Targeted Allele Detail

Summary

• Symbol: Septin5^tm1Bld
• Name: septin 5; targeted mutation 1, Antonio Baldini
• MGI ID: MGI:3640090
• Synonyms: Cdcrel1-, Cdcrel1^tm1Bld
• Gene: Septin5 Location: Chr16:18440561-18448688 bp, - strand Genetic Position: Chr16, 11.53 cM
• Alliance: Septin5^tm1Bld page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:67409
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2-4 of Sept5 were replaced with an Hprt3' chromosome engineering cassette in a targeting vector. AB2.2 embryonic stem cells that were double-targeted in trans were used to create knockout mice. (J:67409)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Septin5 Mutation: 27 strains or lines available

References

• Original: J:67409 Lindsay EA, et al., Tbx1 haploinsufficiency in the DiGeorge syndrome region causes aortic arch defects in mice. Nature. 2001 Mar 1;410(6824):97-101
• All: 3 reference(s)