Slfn1^tm1Hed
Targeted Allele Detail

Summary

• Symbol: Slfn1^tm1Hed
• Name: schlafen 1; targeted mutation 1, Stephen M Hedrick
• MGI ID: MGI:3640337
• Synonyms: Slfn1^-
• Gene: Slfn1 Location: Chr11:83007675-83013496 bp, + strand Genetic Position: Chr11, 50.3 cM
• Alliance: Slfn1^tm1Hed page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:51308
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The single coding exon for the gene was replaced with a tk-neo. RT-PCR confirmed the absence of transcript in mutants. (J:51308)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slfn1 Mutation: 22 strains or lines available

References

• Original: J:51308 Schwarz DA, et al., Schlafen, a new family of growth regulatory genes that affect thymocyte development. Immunity. 1998 Nov;9(5):657-68
• All: 1 reference(s)