Atmin^gpg6
Chemically induced Allele Detail

Summary

• Symbol: Atmin^gpg6
• Name: ATM interactor; gasping 6
• MGI ID: MGI:3640783
• Gene: Atmin Location: Chr8:117670132-117687184 bp, + strand Genetic Position: Chr8, 63.37 cM
• Alliance: Atmin^gpg6 page

Mutation origin

• Strain of Origin: BALB/cAnN

Mutation description

• Allele Type: Chemically induced (ENU) (Null/knockout)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to A point mutation in the third zinc finger domain that results in the amino acid susbtitution of cystine for serine at position 183 (C183S). This mutation is predicted to disrupt zinc binding and the ability of the protein to act as a transcription factor. (J:211696)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	31 assay results
In Structures Affected by this Mutation:	13 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Atmin Mutation: 38 strains or lines available

References

• Original: J:145068 Ermakov A, et al., Mouse mutagenesis identifies novel roles for left-right patterning genes in pulmonary, craniofacial, ocular, and limb development. Dev Dyn. 2009 Feb 22;238(3):581-594
• All: 4 reference(s)