Fbxo5^tm1Dlim
Targeted Allele Detail

Summary

• Symbol: Fbxo5^tm1Dlim
• Name: F-box protein 5; targeted mutation 1, Dae-Sik Lim
• MGI ID: MGI:3640940
• Synonyms: emi1-
• Gene: Fbxo5 Location: Chr10:5749155-5755465 bp, - strand Genetic Position: Chr10, 1.91 cM
• Alliance: Fbxo5^tm1Dlim page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:110317
• Parent Cell Line: AK7 (ES Cell)
• Strain of Origin: 129S4/SvJaeSor

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 2 was replaced with a pgk-puromycin resistance cassette via homologous recombination. (J:110317)

Expression

In Mice Carrying this Mutation:	3 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fbxo5 Mutation: 26 strains or lines available

References

• Original: J:110317 Lee H, et al., Mouse emi1 has an essential function in mitotic progression during early embryogenesis. Mol Cell Biol. 2006 Jul;26(14):5373-81
• All: 1 reference(s)