Enpp2^tm1.1Whm
Targeted Allele Detail

Summary

• Symbol: Enpp2^tm1.1Whm
• Name: ectonucleotide pyrophosphatase/phosphodiesterase 2; targeted mutation 1.1, Wouter H Moolenaar
• MGI ID: MGI:3640942
• Gene: Enpp2 Location: Chr15:54702297-54816284 bp, - strand Genetic Position: Chr15, 21.6 cM, cytoband D2
• Alliance: Enpp2^tm1.1Whm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:110324
• Parent Cell Line: IB10/E14IB10 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exons 6 and 7 were flanked with loxP sites via homologous recombination. Cre mediated recombination then excised these exons. (J:110324)

Expression

In Mice Carrying this Mutation:	14 assay results
In Structures Affected by this Mutation:	7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Enpp2 Mutation: 79 strains or lines available

References

• Original: J:110324 van Meeteren LA, et al., Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development. Mol Cell Biol. 2006 Jul;26(13):5015-22
• All: 4 reference(s)