Mos^tm1Gvw
Targeted Allele Detail

Summary

• Symbol: Mos^tm1Gvw
• Name: Moloney sarcoma oncogene; targeted mutation 1, George F Vande Woude
• MGI ID: MGI:3640947
• Synonyms: MOS^-
• Gene: Mos Location: Chr4:3870658-3872105 bp, - strand Genetic Position: Chr4, 2.16 cM, cytoband A1-A2
• Alliance: Mos^tm1Gvw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:34085
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A replacement vector was used to insert a neo cassette into the mos gene coding sequence. (J:34085)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mos Mutation: 21 strains or lines available

References

• Original: J:34085 Choi T, et al., The Mos/mitogen-activated protein kinase (MAPK) pathway regulates the size and degradation of the first polar body in maturing mouse oocytes. Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):7032-5
• All: 1 reference(s)