Myh9^{Gt(RRE342)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Myh9^{Gt(RRE342)Byg}
• Name: myosin, heavy polypeptide 9, non-muscle; gene trap RRE342, BayGenomics
• MGI ID: MGI:3641195
• Synonyms: Myh9^{Gt(pGT2Lxf)4Byg}
• Gene: Myh9 Location: Chr15:77644788-77726315 bp, - strand Genetic Position: Chr15, 36.81 cM
• Alliance: Myh9^{Gt(RRE342)Byg} page

Mutation origin

• Mutant Cell Line: RRE342
• Germline Transmission: Earliest citation of germline transmission: J:110432
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT2Lxf Vector Type: gene trap
• A gene trap vector, pGT2Lxf, containing a Betageo was inserted between exon 1 and 2. (J:110432)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  RRE342	CC249439 ; (MGI Seq Detail)	5' RACE	Chr15:77726159-77726341 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  279 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myh9 Mutation: 219 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:110432 Parker LL, et al., Absence of hearing loss in a mouse model for DFNA17 and MYH9-related disease: The use of public gene-targeted ES cell resources. Brain Res. 2006 May 26;1091(1):235-42
• All: 2 reference(s)