Sox6^tm2.2Vlf
Targeted Allele Detail

Summary

• Symbol: Sox6^tm2.2Vlf
• Name: SRY (sex determining region Y)-box 6; targeted mutation 2.2, Veronique Lefebvre
• MGI ID: MGI:3641205
• Synonyms: Sox6^fl-
• Gene: Sox6 Location: Chr7:115070107-115638031 bp, - strand Genetic Position: Chr7, 61.29 cM
• Alliance: Sox6^tm2.2Vlf page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:110147
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 2 was flanked by a single loxP site and an frt flanked neo followed by a single loxP site. Cre mediated recombination then removed exon 2 and the neo cassette (J:110147)

Expression

In Mice Carrying this Mutation:	6 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sox6 Mutation: 60 strains or lines available

References

• Original: J:110147 Dumitriu B, et al., Generation of mice harboring a Sox6 conditional null allele. Genesis. 2006 May;44(5):219-24
• All: 4 reference(s)