Igh-J^tm1Khyk
Targeted Allele Detail

Summary

• Symbol: Igh-J^tm1Khyk
• Name: immunoglobulin heavy chain, joining region; targeted mutation 1, Kyoko Hayakawa
• MGI ID: MGI:3641272
• Synonyms: Vh11⁺ NeoR^-
• Gene: Igh-J Location: unknown Genetic Position: Chr12, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:109979
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to insert a VH11DHJH1 gene segment into the locus, with a floxed neo. The neo was subsequently removed via cre-mediated recombination. (J:109979)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Igh-J Mutation: 13 strains or lines available

References

• Original: J:109979 Wen L, et al., Association of B-1 B cells with follicular dendritic cells in spleen. J Immunol. 2005 Jun 1;174(11):6918-26
• All: 4 reference(s)