Dmbx1^tm2Aoh
Targeted Allele Detail

Summary

• Symbol: Dmbx1^tm2Aoh
• Name: diencephalon/mesencephalon homeobox 1; targeted mutation 2, Akihira Ohtoshi
• MGI ID: MGI:3641327
• Synonyms: Dmbx1^tG
• Gene: Dmbx1 Location: Chr4:115772316-115797123 bp, - strand Genetic Position: Chr4, 53.07 cM
• Alliance: Dmbx1^tm2Aoh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:110604
• Parent Cell Line: PC3 (ES Cell)
• Strain of Origin: 129S4/SvJae-Tg(Prm-cre)70Og

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A vector encoding a splice acceptor, IRES, and bovine Mapt EGFP fusion protein was inserted into intron 1 via homologous recombination. GFP expression reiterates endogenous expression and is targeted to axons. (J:110604)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dmbx1 Mutation: 20 strains or lines available

References

• Original: J:110604 Ohtoshi A, et al., Generation and maintenance of Dmbx1 gene-targeted mutant alleles. Mamm Genome. 2006 Jul;17(7):744-750
• All: 1 reference(s)