Dmbx1^tm3(cre)Aoh
Targeted Allele Detail

Summary

• Symbol: Dmbx1^tm3(cre)Aoh
• Name: diencephalon/mesencephalon homeobox 1; targeted mutation 3, Akihira Ohtoshi
• MGI ID: MGI:3641328
• Synonyms: Dmnx1^Cre
• Gene: Dmbx1 Location: Chr4:115772316-115797123 bp, - strand Genetic Position: Chr4, 53.07 cM
• Alliance: Dmbx1^tm3(cre)Aoh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:110604
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Dmbx1^tm3(cre)Aoh expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Dmbx1 (MGI:2153518)

• Mutation details: A vector coding for a splice acceptor, IRES, and Cre protein was inserted into intron 1 via homologous recombination. Cre activity is seen in the embryonic diencephalon and mesencephalon and in the postnatal midbrain, cerebellum, medulla oblongata, and spinal cord. (J:110604)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Dmbx1 (mouse) Summary of all recombinase alleles driven by Dmbx1. Comparative matrix view of recombinase activities Alliance mouse Dmbx1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dmbx1 Mutation: 20 strains or lines available

References

• Original: J:110604 Ohtoshi A, et al., Generation and maintenance of Dmbx1 gene-targeted mutant alleles. Mamm Genome. 2006 Jul;17(7):744-750
• All: 3 reference(s)