Bmp2^tm1Vrs
Targeted Allele Detail

Summary

• Symbol: Bmp2^tm1Vrs
• Name: bone morphogenetic protein 2; targeted mutation 1, Vicki Rosen
• MGI ID: MGI:3641368
• Synonyms: Bmp2^c, Bmp2^clc, Bmp2^flox
• Gene: Bmp2 Location: Chr2:133394079-133404805 bp, + strand Genetic Position: Chr2, 65.21 cM
• Alliance: Bmp2^tm1Vrs page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:110615
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The third exon and part of the 3' UTR were flanked by loxP sites. Excision of the floxed segment is predicted to create a non-functional protein. (J:110615)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bmp2 Mutation: 27 strains or lines available

References

• Original: J:110615 Rivera-Feliciano J, et al., Bmp2 instructs cardiac progenitors to form the heart-valve-inducing field. Dev Biol. 2006 Jul 15;295(2):580-8
• All: 11 reference(s)