Tgif1^tm1Pah
Targeted Allele Detail

Summary

• Symbol: Tgif1^tm1Pah
• Name: TGFB-induced factor homeobox 1; targeted mutation 1, Pamela A Hoodless
• MGI ID: MGI:3652354
• Synonyms: Tgif^-
• Gene: Tgif1 Location: Chr17:71151200-71160527 bp, - strand Genetic Position: Chr17, 41.87 cM
• Alliance: Tgif1^tm1Pah page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:109616
• Parent Cell Line: CCE/EK.CCE (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A lacZ-PGK-neo replaced exons 2 and 3. RT-PCR failed to detect transcript in mutants. (J:109616)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tgif1 Mutation: 52 strains or lines available

References

• Original: J:109616 Mar L, et al., Embryonic fibroblasts from mice lacking Tgif were defective in cell cycling. Mol Cell Biol. 2006 Jun;26(11):4302-10
• All: 4 reference(s)