Tg(Ckm-Cd36)1Naa
Transgene Detail

Summary

• Symbol: Tg(Ckm-Cd36)1Naa
• Name: transgene insertion 1, Nada A Abumrad
• MGI ID: MGI:3652419
• Synonyms: MCK-CD36
• Transgene: Tg(Ckm-Cd36)1Naa Location: unknown
• Alliance: Tg(Ckm-Cd36)1Naa page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Ckm-Cd36)1Naa expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  rat

  Cd36 (29184)

  Cd36	(MGI:107899)

• Mutation details: This transgene consists of 1.3 kb of rat Cd36 coding sequence under the control of the regulatory sequences of the mouse creatine kinase gene. Cd36 is specifically expressed in muscle. Muscle tissues show 3-4 fold and 2-4 fold enhanced expression of mRNA and protein, respectively. (J:57650)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:57650 Ibrahimi A, et al., Muscle-specific overexpression of FAT/CD36 enhances fatty acid oxidation by contracting muscle, reduces plasma triglycerides and fatty acids, and increases plasma glucose and insulin. J Biol Chem. 1999 Sep 17;274(38):26761-6
• All: 2 reference(s)