Tcra-J^tm1Jpdv
Targeted Allele Detail

Summary

• Symbol: Tcra-J^tm1Jpdv
• Name: T cell receptor alpha, joining region; targeted mutation 1, Jean-Pierre de Villartay
• MGI ID: MGI:3652545
• Synonyms: TEA^-
• Gene: Tcra-J Location: unknown Genetic Position: Chr14, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:77518
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting construct was designed to delete 2.3 kb of sequence extending from the TEA promoter to the Jalpha61 segment, leaving intact its RSS. (J:77518)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tcra-J Mutation: 0 strains or lines available

References

• Original: J:77518 Villey I, et al., Defect in rearrangement of the most 5' TCR-J alpha following targeted deletion of T early alpha (TEA): implications for TCR alpha locus accessibility. Immunity. 1996 Oct;5(4):331-42
• All: 1 reference(s)