Nr5a1^tm3Klp
Targeted Allele Detail

Summary

• Symbol: Nr5a1^tm3Klp
• Name: nuclear receptor subfamily 5, group A, member 1; targeted mutation 3, Keith L Parker
• MGI ID: MGI:3652587
• Synonyms: SF-1^-
• Gene: Nr5a1 Location: Chr2:38582668-38604554 bp, - strand Genetic Position: Chr2, 24.42 cM
• Alliance: Nr5a1^tm3Klp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:28763
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Nucleotide substitutions
• Mutation details: A targeting vector was designed to convert the translation initiation codon from methionine to isoleucine. The mutation was expected to abolish expression of any functional protein. (J:28763)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nr5a1 Mutation: 30 strains or lines available

References

• Original: J:28763 Luo X, et al., Steroidogenic factor 1 is the essential transcript of the mouse Ftz-F1 gene. Mol Endocrinol. 1995 Sep;9(9):1233-9
• All: 1 reference(s)