Fgf23^tm1Sliu
Targeted Allele Detail

Summary

• Symbol: Fgf23^tm1Sliu
• Name: fibroblast growth factor 23; targeted mutation 1, Shiguang Liu
• MGI ID: MGI:3652903
• Synonyms: Fgf23^-, FGF23-eGFP⁺
• Gene: Fgf23 Location: Chr6:127049865-127058371 bp, + strand Genetic Position: Chr6, 61.92 cM
• Alliance: Fgf23^tm1Sliu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:110579
• Parent Cell Line: EF1 (ES Cell)
• Strain of Origin: 129S/SvEv x C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to insert an eGFP-neo cassette to replace immediately after the ATG in exon 1. (J:110579)

Disease models

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fgf23 Mutation: 18 strains or lines available

References

• Original: J:110579 Liu S, et al., Pathogenic role of Fgf23 in Hyp mice. Am J Physiol Endocrinol Metab. 2006 Jul;291(1):E38-49
• All: 11 reference(s)